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Note | Regular issue | Vol 48, No. 12, 1998, pp.2637-2641
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8303
A New Efficient Synthesis of 6-Nitroquipazine

Byoung Se Lee, Byung Chul Lee, Jong-Gab Jun, and Dae Yoon Chi*

*Department of Chemistry and Chemical Dynamic Center, Inha University, 253, Yonghyundong Namgu, Inchon 402-751, Korea


A convenient and regioselective synthesis of 6-nitroquipazine from hydrocarbostyril in three steps is described. This synthetic route involved a nitration, a chlorination followed by aromatization, and an aromatic substitution reaction.