Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Regular issue | Vol 51, No. 1, 1999, pp.157-160
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8344
An SNAr-based Preparation of 1-(2-, 3-, and 4-Pyridyl)indoles Using Potassium Fluoride/Alumina

William J. Smith III and J. Scott Sawyer*

*Lilly Reserach Laboratories, Eli Lilly & Company, Lilly Corporate Center, Indianapolis, IN 46285-4813, U.S.A.


The reaction of indole with 2-, 3-, and 4-halopyridines in the presence of potassium fluoride/alumina and 18-crown-6 in DMSO at 120 °C is effective in producing 1-(2-, 3-, and 4-pyridyl)indoles in moderate to good yields.