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Communication | Regular issue | Vol 51, No. 1, 1999, pp.9-12
Published online, 1st January, 1970■ An Improved Synthesis of the ABC Ring Model of Ecteinascidins
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8358
■ An Improved Synthesis of the ABC Ring Model of Ecteinascidins
Naoki Saito, Hiroshi Kamayachi, Masashi Tachi, and Akinori Kubo*
*Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan
Abstract
An improved synthesis of 1,2,3,4,5,6-hexahydro-1,5-imino-9-methoxy-3,8,11-trimethyl-4-oxo-3-benzazocine (6) as an ABC ring model compound of ecteinascidins from 3-(4-methoxy-3-methylphenylmethyl)-1-methyl-2,5-piperazinedione 3 is described.
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