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Note | Regular issue | Vol 51, No. 3, 1999, pp.617-625
Published online, 1st January, 1970
DOI: 10.3987/COM-98-8420
Pyridazines, 88. On the Attack of S-Nucleophiles at 3,6-Disubstituted N-Methyl-N-phenylpyridazine-4-carboxamide

Gottfried Heinisch, Barbara Matuszczak,* Kurt Mereiter, and Jens C. Wilke

*Institut für Organische und Pharmazeutisch Chemie, Universität Innsbruck, Innrain 52, A-6020 Innsbruck , Austria

Abstract

Reactions of 3,6-dichloro-N-methyl-N-phenylpyridazine-4-carboxamide with S-nucleophiles (2-amino-thiophenol, benzyl mercaptan) were studied, structural elucidation of the reaction products was achieved by means of X-Ray analysis and NMR experiments (NOE difference spectroscopy), respectively.