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Note | Regular issue | Vol 51, No. 12, 1999, pp.2983-2989
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8699
Synthesis of Optically Active 2-Piperidylglycine

Hyun-kyu Chung, Hyung-woo Kim, and Kyoo-Hyun Chung*

*Department of Chemistry, Inha University, 253, Yonghyundong Namgu, Inchon 402-751, Korea

Abstract

Both chiral threo- and erythro-2-piperidylglycines were synthesized from racemic 2-[(N-benzyloxycarbonyl)piperidin-2-yl]ethanoic acid. (4S,5S)-4-Methyl-5-phenyl-2-oxa-zolidinone was used as a chiral auxiliary in the resolution and azidation.