Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 53, No. 3, 2000, pp.599-612
Published online, 1st January, 1970
DOI: 10.3987/COM-99-8777
Hydrogenation Derivatives of Neo-clerodanes and Their Antifeedant Activity

Maurizio Bruno, Sergio Rosselli, Ivana Pibiri, Franco Piozzi,* and Monique S. J. Simmonds

*Department of Organic Chemistry, Palermo University, Viale delle Scienze-Parco d’Orleans II, 90128 Palermo, Italy


Hydrogenation of some natural neo-clerodanes on 10% Pd/C resulted in the saturation of the furan ring and in some cases hydrogenolysis of the epoxide system and or γ-lactone ring. Overall, reduction of the furan ring found in the natural compounds resulted in a decrease in the antifeedant activity of the compounds against the lepidopteran pests, Heliocoverpa armigera and Spodoptera frugiperda. However, two of the most active derivatives had both the furan ring and the lactone ring hydrogenated but the epoxide intact.