HETEROCYCLES

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

■ A Synthesis of Benzocarbazole Derivatives by Thermolysis

Tetsuji Kametani,* Toshio Suzuki, Kimio Takahashi, and Keiichiro Fukumoto

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

A thermal reaction of indolylmagnesium bromide (1) with 1- cyano-4,5-dimethoxybenzocyclobutene (2) gave a mixture of 6-cyano-5a,6,11,11a-tetrahydro-8,9-dimethoxy-5H-benzo[b]carbasole (3a) and 6-cyano-5a,6,11,11a-tetrahydro-9-hydroxy-8-methaxy-5H-benzo[b]carbazole (4). Compound (3a) was easily converted to 6-cyano-8,9-dimethoxy-5H-benzo[b]carbazole (6) by dehydrogenation on 30 % Pd-C.