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Communication | Regular issue | Vol 3, No. 2, 1975, pp.139-142
Published online, 1st January, 1970
DOI: 10.3987/R-1975-02-0139
Biotransformnation of (±)-Reticuline into (±)-Coreximine with Rat Liver

Tetsuji Kametani,* Makoto Takemura, Keiichi Takahashi, Masataka Ihara, and Keiichiro Fukumoto

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

The biotransformation of (±)-reticuline (1) inta (±)-coreximine (2) in the rat and with homogenised rat liver was demonstrated by tracer experiments with (±)-[N-14CH3]reticuline (1).