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Communication | Regular issue | Vol 3, No. 2, 1975, pp.171-177
Published online, 1st January, 1970
DOI: 10.3987/R-1975-02-0171
An Improved Synthesis of the Pyridocarbazole Indole Alkaloid Olivacine

James P. Kutney* and David S. Grierson

*Department of Chemisry, University of British Columbia, Vancouver 8, V5T 1W5, Canada


An improved synthesis of the alkaloid olivacine (I) has been developed. Employing tryptophol (III) as starting material, the synthetic sequence provides, in three high-yielding steps, the important aldehyde intermediate X. The latter has been previously converted in an efficient manner to the desired alkaloid.