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Communication | Regular issue | Vol 4, No. 10, 1976, pp.1675-1680
Published online, 1st January, 1970
DOI: 10.3987/R-1976-10-1675
Michael Additions of Indoles to 2-Oxoindolin-3-ylidene Ketones

Akinori Kubo,* Tatsuya Nakai, and Toshikazu Nozoye

*Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan

Abstract

Michael-type additions to (E)-2-oxoindolin-3-ylidene ketones (1) and indoles (2) gave rise to C-1’ (3) and/or C-3 (4) adducts depending on the oxindolic N-substituents and the C-1’ adducts(3) were converted into new 9H-pyridazino[3,4-b]indole derivativeg (6).