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Review | Regular issue | Vol 6, No. 9, 1977, pp.1377-1439
Published online, 1st January, 1970
DOI: 10.3987/R-1977-09-1377
Some Recent Work on Protoberberines and Tetrahydroprotoberberines — A Review

Bantwal R. Pai,* Kuppuswamy Nagarajan, Hosbett Suguna, and Sanlaran Natarajan

*Department of Chemistry, Presidency College, Madras 600005, India


This review is dedicated to Professor Tetsuji Kametani on his completion of 60 years, the greater part of which he dedicated to enriching our knowledge of the chemistry of alkaloids in general and isoquinoline alkaloids in particular. During the last one decade and more, there has been a continuous stream of publications from his laboratory dealing with various aspects of isoquinoline alkaloid chemistry. We owe a debt of gratitude to him and his colleagues for their rich contributions. mere has been a vigorous school of research in Japan working on isoquinoline alkaloids and therefore, we thought it appropriate to choose the above subject as a token of tribute to Professor Kametani, his cmrkers and all our other Japanese colleagues who have been working in the field of alkaloids. This article has for its background the excellent reviews of Jeffs (P.W. Jefis, "The Alkaloids", ed. by R.H.F. Manske, Academic Press, New York, 1967, V01.9, pp.41-115) and Shamma (M. Shamma, "The Isoquinoline Alkaloids", Academic Press, New York, 1972, pp.268-314). It is by no means exhaustive and only certain aspects of protoberberine chemistry are being highlighted here. The authors may be pardoned if much interesting material has been left out.