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Communication | Regular issue | Vol 6, No. 12, 1977, pp.1999-2004
Published online, 1st January, 1970
DOI: 10.3987/R-1977-12-1999
■ The Synthesis of Some 2-Substituted 5-Nitropyrimidines

Derek T. Hurst* and John Christophides

*School of Analytical and Biological Chemistry, Kingston Polytechnic, Kingston-on-Thames, KT1 2EE, U.K.

Abstract

The synthesis of 2-(fur-2-yl)-, 2-(5-nitrofur-2-yl)-, 2-(N-morpholinyl)-, and 2-methylsulphonyl-5-nitropyrimidine is described together with the synthesis of some other 2-(substituted) 5-nitropyrimidines. 2-(N-Morpholinyl)- and 2-(fur-2-yl)-5-nitropyrimidine were reduced to the corresponding 5-amino derivatives.