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Communication | Regular issue | Vol 12, No. 12, 1979, pp.1535-1538
Published online, 1st January, 1970
DOI: 10.3987/R-1979-12-1535
Potential Carcinostatics VI. Biologically Active 5-Fluorouracil Derivatives of 2-Oxo-2,5-dihydrofuran

Gerrit-Jan Koomen, Frans van Alewijk, Direk Blok, and Upendra K. Pandit*

*Laboratory of Organic Chemistry, University of Amsterdam, Nieuwe Achtergracht 129,1018 WS Amsterdam, The Netherlands

Abstract

1-(2-Oxo-2,5-dihydro-5-furyl)-5-fluorouracil derivatives have been synthesized and shown to be active in the P-388 mouse leukemia test system.