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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 14, No. 3, 1980, pp.277-280
Published online, 1st January, 1970■ A Novel Synthesis of Indoel Derivatives
Published online, 1st January, 1970
DOI: 10.3987/R-1980-03-0277
■ A Novel Synthesis of Indoel Derivatives
Tetsuji Kametani,* Tatsushi Ohsawa, and Masataka Ihara
*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan
Abstract
1-Acetyl-2,3-dihydro-5,6-dimethoxy-1H-indole (13) was synthesized by cyclization of N-(2-bromo-4,5-dimethoxyphenethyl)-acetamide (6) using sodium hydride and cuprous halide in dimethylformamide. Indoles (14, 15 and 16) were prepared in a similar manner from the corresponding amides (8 and 10) and the carbamate (12). Under similar reaction conditions, phenylacetamides (20 and 21) afforded the oxindoles (22 and 23).
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