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Communication | Regular issue | Vol 14, No. 3, 1980, pp.285-286
Published online, 1st January, 1970
DOI: 10.3987/R-1980-03-0285
Facile Oxidation of 2-Oxo-1,4,6-trisubstituted 1,2,3,6-Tetrahydropyrimidines with Chloranil

Choji Kashima,* Akira Katoh, Yuko Yokota, and Yoshimori Omote

*Department of Chemistry, University of Tsukuba, 1-1-1 Ten-nodai, Tsukuba-shi, Ibaraki, 305-8571, Japan


2-Oxo-1,4,6-trisubstituted 1,2,3,6-tetrahydropyrimidines (1a-1h) were easily oxidized with 2,3,5,6-tetrachloro-1,4-benzoquinone(chloranil) to afford the corresponding 1,4,6-trisubstituted 2(1H)-pyrimidinones (2) in good yields.