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Communication | Regular issue | Vol 14, No. 3, 1980, pp.291-293
Published online, 1st January, 1970
DOI: 10.3987/R-1980-03-0291
The Reaction of O-Ethylsuccinimide with Aryllithium Compounds: An Efficient Method for the Introduction of 3-Ethoxycarbonylpropionyl Group to Aromatic Compounds

Tatsuo Nagasaka,* Fumiko Hamaguchi, Naganori Ozawa, Yoshiyuki Kosugi, and Sadao Ohki

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


O-Ethyl succinimide (I) was found to be an efficient reagent for the introduction of 3-ethoxycarbonylpropionyl group (-COCH2CH2COOEt) to aromatic compounds by a single operation under mild conditions.