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Report | Regular issue | Vol 14, No. 3, 1980, pp.311-313
Published online, 1st January, 1970
DOI: 10.3987/R-1980-03-0311
Direct Synthesis of Some 9-Aminoalkylacridines from 9-Aminoacridine Using Phase Transfer Catalysis

Jean Pierre Galy, José Elguero, Emile Jean Vincent, Anna-Marie Galy, and Jaques Barbe*

*Laboratoire de Chimie Minérale, U. E. R. de Pharmacie, Université de la Mediterranee de Marseille, 27, Bd Jean-Moulin 13385 Marseille Cedex 5, France

Abstract

A new method of preparation of 9-aminoalkyl acridines is described which avoid the use of 9-chloroacridine. Proton n.m.r. in trifluoroacetic acid easily differentiates 9-aminoalkyl from 9-amino 10-alkyl acridinium salts. Two dialkyl iminoacridanes have been obtained.