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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 16, No. 4, 1981, pp.599-603
Published online, 1st January, 1970■ Synthesis of 1-Oxa Analogues of Naturally Occurring Cephalosporins and Cephamycins
Published online, 1st January, 1970
DOI: 10.3987/R-1981-04-0599
■ Synthesis of 1-Oxa Analogues of Naturally Occurring Cephalosporins and Cephamycins
Yuji Sendo,* Toshiro Konoike, Masayuki Murakami, and Mitsuru Yoshioka
*Shionogi Research Laboratories, Shionogi & Co. Ltd., Fukushima-ku, Osaka 553-0002, Japan
Abstract
The title compounds 15a-c and 16a-c were synthesized from a 3-exomethylene-1-oxacepham compound 4. Its chlorohydroxylation provided a key intermediate 5e in synthesis of the 3’-oxygen-functionalized 1-oxacephems.
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