Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 16, No. 4, 1981, pp.599-603
Published online, 1st January, 1970
DOI: 10.3987/R-1981-04-0599
Synthesis of 1-Oxa Analogues of Naturally Occurring Cephalosporins and Cephamycins

Yuji Sendo,* Toshiro Konoike, Masayuki Murakami, and Mitsuru Yoshioka

*Shionogi Research Laboratories, Shionogi & Co. Ltd., Fukushima-ku, Osaka 553-0002, Japan


The title compounds 15a-c and 16a-c were synthesized from a 3-exomethylene-1-oxacepham compound 4. Its chlorohydroxylation provided a key intermediate 5e in synthesis of the 3’-oxygen-functionalized 1-oxacephems.