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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 16, No. 4, 1981, pp.605-608
Published online, 1st January, 1970■ An Efficient Synthesis of cis-Oxabicyclo[3.3.0]oct-6-en-3-one
Published online, 1st January, 1970
DOI: 10.3987/R-1981-04-0605
■ An Efficient Synthesis of cis-Oxabicyclo[3.3.0]oct-6-en-3-one
Seiichi Takano,* Chiyoshi Kasahara, and Kunio Ogasawara
*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan
Abstract
An efficient synthesis of a prostaglandin synthon (±)-cis-oxabicyclo[3.3.0]oct-6-en-3-one (1) has been developed using cyclopentadiene (2) as starting material. Employing the same methodology optically active (1) is also synthesized in low optical purity.
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