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Communication | Regular issue | Vol 16, No. 8, 1981, pp.1325-1328
Published online, 1st January, 1970
DOI: 10.3987/R-1981-08-1325
Dechlorination of Some Chloropyrazines and Their N-Oxides

Yasuo Akita and Akihiro Ohta*

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


By heating with sodium formate and tetrakis(triphenylphosphine)palladium, chloropyrazines were converted to the parent pyrazines in satisfactory yields. The chlorine atoms of chloropyrazine N-oxides could also be removed, leaving the N-O group.