HETEROCYCLES
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Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 16, No. 11, 1981, pp.1873-1877
Published online, 1st January, 1970■ Synthesis of Quinoline Alkaloids and Related Compounds. Synthesis of Zanthophylline and a New Synthesis of 3,3-Bis(γ,γ-Dimethylallyl)-N-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinoline
Published online, 1st January, 1970
DOI: 10.3987/R-1981-11-1873
■ Synthesis of Quinoline Alkaloids and Related Compounds. Synthesis of Zanthophylline and a New Synthesis of 3,3-Bis(γ,γ-Dimethylallyl)-N-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinoline
Pietro Venturella,* Aurora Bellino, and Maria Luisa Marino
*Instituto de Chimica Organica , Facolta de Scienze, Università digli Studi di Palermo, 20 via Archirafi, 90123 Palermo, Italy
Abstract
The alkaloid zanthophylline (I) was synthesized from the 8-methoxyflindersine (III) by N-alkylation with chloromethylacetate. The 3,3-bis(γ,γ-dimethylallyl)-N-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinoline (II) was also synthesized by direct methylation of (V).
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