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Communication | Regular issue | Vol 19, No. 1, 1982, pp.27-29
Published online, 1st January, 1970
DOI: 10.3987/R-1982-01-0027
A Short Synthesis of 1-Phenyl-3-oxo-octahydroisoquinolines

Kai S. Ng, Peter S. Rutledge, and Paul D. Woodgate

*Department of Chemistry, University of Auckland, Private Bag 92019, Auckland, New Zealand


Equimolar amounts of benzaldehyde and 1-cyclohexenylacetonitrile react with P2O5 — methanesulfonic acid to give a mixture isomeric 1-phenyl-3-oxo-octahydroisoquinolines in good yield.