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Communication | Regular issue | Vol 19, No. 2, 1982, pp.249-252
Published online, 1st January, 1970
DOI: 10.3987/R-1982-02-0249
Synthesis of 1,2-Diphenylpyrrolo[1,2-a]quinazolines

Jiroh Horiuchi, Masatoshi Yamato, Nobuya Katagiri, and Tetsuzo Kato

*Pharmaceutical Institute, Pharmaceutical Institute, Aobayama, Sendai 980-8578, Japan


Heating of 2-aminobenzamide (1) with benzoin (4) in the presence of anhydrous zinc chloride gave 2-(1-benzoylbenzylamino)benzamide (5a) which, on treatment with acetic anhydride, was transformed to 1,2-diphenyl-4,5-dihydropyrrolo-[1,2-a]quinazolin-5-one (6).