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Communication | Regular issue | Vol 19, No. 6, 1982, pp.1019-1022
Published online, 1st January, 1970
DOI: 10.3987/R-1982-06-1019
Rearrangement of N-Hydroxy-2-azetidinones to 5-Isoxazolidinones

Tohru Hirose, Katsumi Chiba, Shinsaku Mishio, Junji Nakano, and Hitoshi Uno

*Dainippon Pharmaceutical Co., LTD., Enoki 33-94, Suita, Osaka 564, Japan


N-Hydroxy-2-azetidinodes (IV) underwent a new rearrangement to 5-isoxazolidinones (V). By use of this rearrangement, one (Ve) of isomers of cycloserine was synthesized.