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Communication | Regular issue | Vol 19, No. 8, 1982, pp.1381-1384
Published online, 1st January, 1970
DOI: 10.3987/R-1982-08-1381
Structures of Mahuannin A and B, Hypotensive Principles of Ephedra Roots

Hiroshi Hikino, Nobuyoshi Shimoyama, Yoshimasa Kasahara, Michiko Takahashi, and Chohachi Konno

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

Two novel bisflavanols, mahuannin A and B, exhibiting the hypotensive activity have been isolated from the crude drug “mao-kon”, the roots of Ephedra plants. The stereostructures of mahuannin A and B, advanced on the basis of chemical and physical evidence, have been elucidated as those represented by formulas I and II.