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Communication | Regular issue | Vol 19, No. 9, 1982, pp.1595-1596
Published online, 1st January, 1970
DOI: 10.3987/R-1982-09-1595
Ring Transformation of Heterocycles via N-Imide Intermediates: From Nicotine to Hexahydropyrido[3,4-b]1,2-diazocine

Yasumitsu Tamura, Masayoshi Tsunekawa, Hiroyuki Ikeda, and Masazumi Ikeda

*Faculty of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Toyonaka, Osaka 560-0043, Japan


Treatment of the N-amino derivative of nicotine with sodium amide in liquid ammonia gave 2-methylhexahydropyrido[3,4-b]-1,2-diazocine.