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Communication | Regular issue | Vol 19, No. 11, 1982, pp.2037-2040
Published online, 1st January, 1970■ The Synthesis of 7,8-Dimethoxy-1-(3,4-dimethoxybenzyl)-2,3-dihydro-1H-3-benzazepine and Related Compounds
Published online, 1st January, 1970
DOI: 10.3987/R-1982-11-2037
■ The Synthesis of 7,8-Dimethoxy-1-(3,4-dimethoxybenzyl)-2,3-dihydro-1H-3-benzazepine and Related Compounds
Roger F. Newton, Malcorm Sainsbury, and Paul L. R. Stanley
*Glaxo Group Research Limited, Ware, Hertfordshire SG12 0DJ, U.K.
Abstract
The title compound has been synthesised by the acid catalysed cyclisation of 2,3-bis-(3,4-dimethoxyphenyl)propylaminoacetaldehyde diethylacetal. The preparation of 7,8-dimethoxy-1-(3,4-dimethoxybenzylidene-4,5-dihydro-1H-3-benzazepine and its hydrogenation products is also described.
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