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■ Synthesis and Reactivity of 2-Azabicyclo[2.2.1]heptanes, Heptenes and Heptadienes

Dominique Blondet and Christophe Morin

*Unité de Chimie Organique, Départment de Biochimie et de Génétique Moléculaire, ERA/CNRS927, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, Cedex 15, France

Abstract

It is purpose of this review to cover all known methods of preparation of 2-azabicyclo[2.2.1]heptanes, heptenes, and heptadienes. The reactivity of these systems will then be discussed, stressing their synthetic potential as it has already been demonstrated for example in the field of nucleoside antibiotics.