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Review | Regular issue | Vol 19, No. 11, 1982, pp.2155-2182
Published online, 1st January, 1970
DOI: 10.3987/R-1982-11-2155
Synthesis and Reactivity of 2-Azabicyclo[2.2.1]heptanes, Heptenes and Heptadienes

Dominique Blondet and Christophe Morin

*Unité de Chimie Organique, Départment de Biochimie et de Génétique Moléculaire, ERA/CNRS927, Institut Pasteur, 28, rue du Docteur Roux, 75724 Paris, Cedex 15, France


It is purpose of this review to cover all known methods of preparation of 2-azabicyclo[2.2.1]heptanes, heptenes, and heptadienes. The reactivity of these systems will then be discussed, stressing their synthetic potential as it has already been demonstrated for example in the field of nucleoside antibiotics.