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Report | Regular issue | Vol 20, No. 1, 1983, pp.55-58
Published online, 1st January, 1970
DOI: 10.3987/R-1983-01-0055
Facile Synthesis of 2’-Deoxy-2’-arylthiouridines

Akira Matsuda and Tadashi Miyasaka

*School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan


Cleavage of the anhydro linkage of O2,2’-cyclouridine(1a) with o-,m-, and p-substituted thiophenols and β-naphthalenethiol was carried out in dimethylformamide to give the corresponding 2’-deoxy-2’-arylthiouridines(6a-g) in good yields.