Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,320 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 20, No. 4, 1983, pp.593-596
Published online, 1st January, 1970
DOI: 10.3987/R-1983-04-0593
One-Pot Synthesis of Furan Systems Bearing 2-Pyridyl Substituent

Otohiko Tsuge, Koyo Matsuda, and Shuji Kanemasa

*Graduate School of Engineering Sciences, Kyushu University, 6-1, Kasuga-koen, Kasuga 816-8580, Japan

Abstract

The reaction of an anionic intermediate, generated in situ from the lithio derivative of 2-(trimethylsilylmethyl)pyridine and an aromatic nitrile, with α-haloketones such as phenacyl bromide, desyl chloride and 2-bromocyclohexanone provided a route to a one-pot synthesis of rare 2-pyridyl substituted furans. The reaction pathway is also described.