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Report | Regular issue | Vol 20, No. 7, 1983, pp.1331-1334
Published online, 1st January, 1970
DOI: 10.3987/R-1983-07-1331
The Enantioselective Synthesis of (+)-Retronecine, (—)-Platynecine, and (+)-Croalbinecine and Its C-1 Epimer

Heinrich Rüeger and Michael Benn

*Department of Chemistry, The University of Alberta, Calgary, Alberta, T2N, 1N4, Canada

Abstract

The Geissman-Waiss lactone, (+)-6-aza-2-oxabicyclo[3,3,0]octan-2-one, obtained from (2S,4R)-4-hydroxyproline was used as a synthon for the preparation of (+)-retronecine. (-)-platynecine, and (+)-croalbinecine (helifolinecine) and its C-1 epimer.