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Review | Regular issue | Vol 20, No. 12, 1983, pp.2471-2511
Published online, 1st January, 1970
DOI: 10.3987/R-1983-12-2471
Elaboration of the Ethylidene Substituent in the Synthesis of Indole Alkaloids

Joan Bosch and Ma Lluïsa Bennasar

*Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Av. de Joan XXIII, s/n, 08028 Barcelona, Spain


Some indole alkaloids have a C-20 ethylidene substituent as a common structural feature. All methods for the elaboration of this exocyclic, E-configurated double bond developed in indole alkaloid synthesis are reviewed.