Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Report | Regular issue | Vol 22, No. 3, 1984, pp.501-504
Published online, 1st January, 1970
DOI: 10.3987/R-1984-03-0501
■ Reactions of 4-Pyrimidinone Derivatives with Methyl Isocyanate: Formation of Pyrimido[1,2-a][1,3,5]triazine-2,4-dione RIng System

Masami Sawada, Yoshiro Furukawa, Yoshio Takai, and Terukiyo Hanafusa*

*The Institute of Scientific and Industrial Research, Osaka University ,8-1, Mihogaoka, Ibaraki, Osaka 567-0047, Japan

Abstract

Base-catalysed reactions of 4-pyrimidinone and 4-quinazolinone with methyl isocyanate gave the compounds with a pyrimido[1,2-a][1,3,5]triazine-2,4-dione ring system (3 and 5, respectively; 1:2-cyclic adducts). In contrast, some uracil derivatives afforded the 1-methylcarbamoyl compounds (7, 1:1-adducts) .