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Report | Regular issue | Vol 22, No. 3, 1984, pp.527-530
Published online, 1st January, 1970
DOI: 10.3987/R-1984-03-0527
5-Fluorouracil Derivatives. VI. Alkylation of 5-Fluorouracil Using the (Octylthio)carbonyl Group as a Protectiong Function

Shoichiro Ozaki,* Yutaka Watanabe, Hiroshi Fujisawa, and Tomonori Hoshiko

*Faculty of Engineering, Ehime University, 3 Bunkyo-cho, Matsuyama, 790-8577 Ehime, Japan


N1- and N3-alkyl-5-fluorouracils are prepared in good yields by the alkylation of 5-fluorouracil protected by the (octylthio)carbonyl group.