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Report | Regular issue | Vol 23, No. 1, 1985, pp.133-137
Published online, 1st January, 1970
DOI: 10.3987/R-1985-01-0133
Reaction of Chloropyrazine N-Oxides with Trimethylaluminum

Akihiro Ohta,* Akira Inoue, Kimie Otshuka, and Tokuhiro Watanabe

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

some 2-chloropyrazine 1- and 4-oxides were submitted to the coupling reaction with trimethylaluminum in the presence of a palladium catalyst. The corresponding 2-methylpyrazine 1- and 4-oxides were obtained in excellent yields.