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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Communication | Regular issue | Vol 23, No. 5, 1985, pp.1081-1084
Published online, 1st January, 1970■ Facile Retro Dieckmann Reaction of 3-Oxo-carbapenam Esters
Published online, 1st January, 1970
DOI: 10.3987/R-1985-05-1081
■ Facile Retro Dieckmann Reaction of 3-Oxo-carbapenam Esters
Johannes G. de Vries,* Gerhard Hauser, and Gerfard Sigmund
*Sandoz Forschungsinstitut, 1235 Wien, Brunnerstraße 59, Austria
Abstract
Bicyclic ketones 1b and 1c reacted with nucleophiles to give azetidinones 4. Azetidinone 4a was deprotected to give 5, which was antibacterially inactive.
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