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Communication | Regular issue | Vol 23, No. 10, 1985, pp.2505-2508
Published online, 1st January, 1970
DOI: 10.3987/R-1985-10-2505
Pagicerine — A New Indole Alkaloid from Pagiantha derifera (Pancher et Sébert) Markgraf (Apocynaceae)

Matyse Bert, Geneviève Baudouin, François Tillequin, and Michel Koch*

*U.A. au C.N.R.S.n°484, Faculté des Sciences Pharmaceutiques et Biologiques, Université René Descartes, 4, Avenue de l‘Observatoire, F-75006 Paris, France

Abstract

A new 2-acylindole alkaloid, pagicerine (1) has been isolated from the stem bark of Pagiantha cerifera (Pancher et Sébert) Markgraf. Its structure has been elucidated on the basis of spectroscopic analyses. It is the first indole alkaloid to present an additional tetrahydro-1,3-oxazine ring.