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Report | Regular issue | Vol 23, No. 12, 1985, pp.3095-3098
Published online, 1st January, 1970
DOI: 10.3987/R-1985-12-3095
Saturated Heterocycles. 93. Facile Dehydrogenation and an Unexpected Catalytic Hydrogen Transfer Reaction of 1,2,5,6,7,8-Hexahydroquinazolin-4(3H)-ones

Ferenc Fülöp and Gábor Bernáth*

*Institute of Pharmaceutical Chemistry, University Medical School, Szeged, Hungary

Abstract

2-Phenyl-1,2,5,6,7,8-hexahydroquinazolin-4(3H)-one (2) and the related 2-(3’-cyclohexenyl) derivative (4) were observed to undergo a facile dehydrogenation and an intermolecular catalytic hydrogen transfer in the presence of Pd/C, even in a hydrogen atmosphere.