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Paper | Regular issue | Vol 24, No. 4, 1986, pp.971-977
Published online, 1st January, 1970
DOI: 10.3987/R-1986-04-0971
Facile Synthesis of Styrylquinuclidines

Fiore J. Ricciardi* and Peter H. Doukas

*Department of Medical Chemistry, School of Pharmacy, Temple University, 3307 North Broad Street, Philadelphia, Pennsylvania 19140, U.S.A.

Abstract

3- and 2-Quinuclidinecarboxaldehydes, 3 and 12, were prepared by Wittig reaction and DIBAH reduction respectively. These aldehydes were used to prepare the corresponding 3- and 2-styrylquinuclidines. 4-7 and 13-16, via Wittig reactions.