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Communication | Regular issue | Vol 24, No. 6, 1986, pp.1541-1547
Published online, 1st January, 1970
DOI: 10.3987/R-1986-06-1541
Trifluoropyruvic Acid Hydrate in Heterocyclic Cynthesis Part III: A Novel Synthesis of 4-(Trifluoromethyl)-oxazolones and Other Related Compounds

Mohamed El-said Mustafa, Akio Takaoka, and Nobuo Ishikawa*

*Department of Chemical Technology, Faculty of Engineering, Tokyo Institute of Technology, 2-12-1,Oh-Okayama, Meguro-ku, Tokyo 152-8552, Japan


Acid-catalyzed reaction of trifluoropyruvic acid hydrate (1) with nitriles is reported. The structure of the resulting compounds is also investigated.