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Communication | Regular issue | Vol 24, No. 7, 1986, pp.1815-1819
Published online, 1st January, 1970
DOI: 10.3987/R-1986-07-1815
The Syntehsis of the Cooked-beef Mutagen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and Its 3-Methyl Isomer

Mark G. Knize and James S. Felton*

*Department of Chemistry and Biochemistry, University of Oklahoma, Nrman, Oklahoma 73019, U.S.A.

Abstract

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a mutagenic compound newly isolated from cooked beef, and its 3-methyl isomer have been synthesized. The spectroscopic data and the mutagenicity of the isomers are compared.