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Communication | Regular issue | Vol 24, No. 8, 1986, pp.2099-2103
Published online, 1st January, 1970
DOI: 10.3987/R-1986-08-2099
Synthesis of the Enantiomers of 7,8-Dimethoxy-7,8-2-phenyl-1,2,4,5-tetrahydro-3-benzazepine

Jürg R. Pfister*

*Institute of Organic Chemistry, Syntex Research, Palo Alto, California 94304, U.S.A.


The chiral 2-phenyltetrahydro-3-benzazepines (R)-8 and (S)-8 were prepared from optically active O-acetylmandeloyl chlorides utilizing a ring closure/ring opening strategy.