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Paper | Regular issue | Vol 26, No. 2, 1987, pp.405-412
Published online, 1st January, 1970
DOI: 10.3987/R-1987-02-0405
Isolation and Structural Studies on the Alkaloids of Rhazya stricta

Atta-ur-Rahman and Sajida Khanum

*H. E. J. Postgraduate Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan


A new alkaloid isorhazicine (2) has been lsolated from the leaves of Rhazya strica The structure and relative stereochemistry have been determined by spectroscopic studies, particularly by NOE difference. COSY-45° and DEPT experiments. Isorhazicine (2) was shown to differ from rhazicine (1) in that it bearss ‘Z’ configuration of the ethylidene group.