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Paper | Regular issue | Vol 26, No. 6, 1987, pp.1503-1515
Published online, 1st January, 1970
DOI: 10.3987/R-1987-06-1503
Heterocycles. 11. Sulfer Analogs of 3-(3-Hydroxyphenyl)-N-n-propylpiperidine

Philip M. Weintraub, Frank P. Miller, and Norbert L. Weich

*Merrell Dow Research Institute, 2110 East Galbraith Road, Cincinnati, Ohio 45215, U.S.A.

Abstract

Analogs of 3-(3-hydroxypheny1)-N-n-propylpiperidine (3-PPP) and 3-(3- hydroxypheny1)-N-(2-phenylethy1)piperidine (phenethyl 3-PP) in which carbon 4 was replaced by sulfur were synthesized and tested for dopamine autoreceptor activity.