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Paper | Regular issue | Vol 26, No. 9, 1987, pp.2381-2384
Published online, 1st January, 1970
DOI: 10.3987/R-1987-09-2381
■ Synthesis of 5-Oxa-13-thiaprotoberberine Derivatives

János Szabó, Gábor Bernáth, and Pál Sohár

*Institute of Pharmaceutical Chemistry, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary

Abstract

With phosgene or aliphatic aldehydes, 6,7-dimethoxy-2- (2-hydroxyphenyl)-3,4-dihydro-2H-1,3-benzothiazine afforded novel 10,11-dimethoxy-6H,8H,13aH[1,3]benzoxazino[4,3-b][1,3]benzothiazine derivatives, members of a new heterocyclic ring system.