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Paper | Regular issue | Vol 26, No. 11, 1987, pp.2921-2939
Published online, 1st January, 1970
DOI: 10.3987/R-1987-11-2921
Facile Synthesis of Some Oxazolopyridines and Their N-Oxides via Intramolecular Cyclization

Yoshinobu Tagawa and Yoshinobu Goto

*Faculty of Pharmaceutical Sciences, Fukuoka University, Nakamura, Jonan-ku, Fukuoka, 814-0180, Japan

Abstract

A convenient synthesis of 3-methylisoxazola[4,5-b]-pyridine 2, 2-methyloxazolo[4,5-b]pyridine 4 and their N-oxides (12, 11 and 18) is reported. The configurations of the oximes used for the synthesis of the compounds described above are discussed through chemical and spectral studies.