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Paper | Regular issue | Vol 26, No. 12, 1987, pp.3181-3191
Published online, 1st January, 1970
DOI: 10.3987/R-1987-12-3181
Synthesis of Arglecin

Akihiro Ohta, Yutaka Aoyagi, Yohko Kurihara, Kayo Yuasa, Makoto Shomazaki, Teruo Kurihara, and Hiroshi Miyamae

*Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


Arglecin (1) and its analogue, 6-(3-aminopropy1)-3-isobutyl-2(1H)-pyrazinone (2). were synthesized from DL-alanyl-leucyl anhydride in several steps.