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Review | Regular issue | Vol 57, No. 7, 2002, pp.1353-1365
Published online, 1st January, 1970
DOI: 10.3987/REV-02-549
Methods for Preparation of γ- and δ-Oxoacids as Useful Synthons for Heterocycles

Ferenc Csende and Géza Stájer*

*Institute of Pharmaceutical Chemistry, University of Szeged, POB 121, H-6720 Szeged, Eötvös u. 6, Hungary

Abstract

Numerous synthetic routes have been recommended for the preparation of γ- and δ-oxo acids. The present paper collects methods which need simple starting materials, procedures and conditions. Many examples are presented, comparing the preparations of aliphatic, cycloalkane, aromatic and hetero ring-containing oxo acids from the aspects of yield, regio- and diastereoselectivity.