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Review | Regular issue | Vol 48, No. 8, 1998, pp.1673-1724
Published online, 1st January, 1970
DOI: 10.3987/REV-98-500
Five Nx-Methyladenines: Their Chemistry, Physicochemical Properties, and Biological Activities

Tozo Fujii* and Taisuke Itaya

*Faculty of Pharmaceutical Scicences, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-0934, Japan

Abstract

Various mono-N-substituted adenines are represented by the corresponding five possible isomers of Nx-methyladenine, namely, 9-methyladenine (2), 7-methyladenine (3), 3-methyladenine (4), 1-methyladenine (5), and N6-methyladenine (6). The chemistry, physicochemical properties, and biological activities of these Nx-methyladenines are reviewed with 366 reference citations.