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Communication | Special issue | Vol 5, No. 1, 1976, pp.19-24
Published online, 1st January, 1970
DOI: 10.3987/S-1976-01-0019
Novel Base-modified Nucleosides

Herman P. M. Thiellier, Gerrit-Jan Koomen, and Upendra K. Pandit*

*Laboratory of Organic Chemistry, University of Amsterdam, Nieuwe Achtergracht 129,1018 WS Amsterdam, The Netherlands


Addition of halocarbenes to uridine derivatives leads to the formation of C5-C6 adducts, which upon heating yield novel 1,3-diazepine nucleosides.